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Bethyl Laboratories
CCDC131 Polyclonal Antibody
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FIGURE: 1 / 1
CCDC131 Antibody (A301-455A) in WB
Detection of human CCDC131 by western blot and immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-CCDC131 antibody (Product # A301-455A) used for WB at 0.04 µg/mL (A) and 1 µg/mL (B) and used for IP at 3 µg/mg lysate. CCDC131 was also immunoprecipitated by rabbit anti-CCDC131 antibodies A301-456A and A301-457A, which recognize downstream epitopes. Detection: Chemiluminescence with exposure times of 10 seconds (A) and 1 second (B)... View More
Product Details
A301-455A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 300 and 350 of human coiled-coil domain containing 131.
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: coiled-coil domain containing 131; Coiled-coil domain-containing protein 131; MGC23401; proline/serine-rich coiled-coil 2; Proline/serine-rich coiled-coil protein 2; unnamed protein product; Zinc finger C3H1 domain-containing protein
Gene Aliases: CCDC131; CSRC2; KIAA0546; PSRC2; ZFC3H1
UniProt ID: (Human) O60293
Entrez Gene ID: (Human) 196441
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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