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Bioss
CCDC139 Polyclonal Antibody
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Product Details
BS-7102R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human PUS10/CCDC139, amino acids 101-200.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: coiled-coil domain containing 139; Coiled-coil domain-containing protein 139; Hup10; pseudouridylate synthase 10; Psi55 synthase; putative tRNA pseudouridine synthase Pus10; tRNA pseudouridine 55 synthase; tRNA pseudouridine synthase Pus10; tRNA pseudouridylate synthase; tRNA-uridine isomerase; unnamed protein product
Gene Aliases: 2810013G11Rik; 4933435A13Rik; AU014648; C77560; CCDC139; DOBI; Hup10; PUS10; RGD1306402
UniProt ID: (Human) Q3MIT2, (Mouse) Q9D3U0
Entrez Gene ID: (Human) 150962, (Rat) 305583, (Mouse) 74467
RNA binding
protein binding
pseudouridine synthase activity
isomerase activity
metal ion binding
primary miRNA binding
tRNA pseudouridine synthase activity
tRNA pseudouridine(55) synthase activity
molecular_function
pivalyl-CoA mutase activity
o-hydroxylaminobenzoate mutase activity
lupeol synthase activity
beta-amyrin synthase activity
baruol synthase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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