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Product Details
13074-2-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
CCK Fusion Protein Ag3725 (1-115 aa encoded by BC008283) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: MNSGVCLCV LMAVLAAGAL TQPVPPADPA GSGLQRAEEA PRRQLRVSQR TDGESRAHLG ALLARYIQQA RKAPSGRMSI VKNLQNLDPS HRISDRDYMG WMDFGRRSAE EYEYPS (1-115 aa encoded by B C008283)
Target Information
Cholecystokinin (CCK) is a neuropeptide hormone and neurotransmitter widely distributed throughout the gastrointestinal (GI) tract and the central nervous system (CNS). Antibodies that react specifically with CCK are useful for the study of the mode of action, differential tissue expression and intracellular and subcellular localization of CCK in the CNS and periphery as well as in neuroendocrine cells of the digestive system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (1-49)-CCK58; CCK; CCK12; CCK18; CCK25; CCK33; CCK39; CCK5; CCK58; CCK7; CCK8; Cholecystokinin; cholecystokinin octapeptide; cholecystokinin triacontatriapeptide; Cholecystokinin-12; Cholecystokinin-18; Cholecystokinin-25; Cholecystokinin-33; Cholecystokinin-39; Cholecystokinin-5; Cholecystokinin-58; Cholecystokinin-58 desnonopeptide; Cholecystokinin-7; Cholecystokinin-8; prepro-cholecystokinin
Gene Aliases: CCK
UniProt ID: (Human) P06307
Entrez Gene ID: (Human) 885
behavioral fear response
neuron migration
release of cytochrome c from mitochondria
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
protein kinase C-activating G-protein coupled receptor signaling pathway
axonogenesis
positive regulation of cell proliferation
positive regulation of glutamate secretion
negative regulation of appetite
positive regulation of protein oligomerization
eating behavior
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of mitochondrial depolarization
regulation of sensory perception of pain
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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