Recommended positive controls: Cyclin-D1-binding protein 1 tansfected 293T cell.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cyclin D-type binding-protein 1; Cyclin-D1-binding protein 1; D-type cyclin-interacting protein 1; grap2 and cyclin D interacting protein; Grap2 and cyclin-D-interacting protein; Human homolog of Maid
Gene Aliases: CCNDBP1; DIP1; GCIP; HHM
UniProt ID: (Human) O95273
Entrez Gene ID: (Human) 23582