|Tested species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide corresponding to residues K(4) P T E Q V S W G L Y S G Y D E E A Y S V G P L P E L C(31) of mouse CCR10.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2, with 1mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:250|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-21617 detects CCR10 in Mouse samples.
PA1-21617 has been successfully used in ELISA, immunocytochemistry, immunohistochemistry (paraffin) and Western blot procedures.
The PA1-21617 immunogen is a synthetic peptide corresponding to residues K(4) P T E Q V S W G L Y S G Y D E E A Y S V G P L P E L C(31) of mouse CCR10.
Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR10 in particular is the receptor for the skin-associated CC chemokine CCL27 (CTACK) as well as the novel chemokine CCL28, which displays chemotactic activity for resting CD4+ and CD8+ T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.