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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Receptors for the CC chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5 and the Duffy blood group antigen. The CC receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. The HIV receptor is composed of two molecules, the CD4 binding receptor and a co receptor. The chemokine receptor CCR5 is one of the co receptors used by primary isolates of HIV1. Extracellular domains of CCR5 are important for HIV entry into the target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
C-C motif chemokine receptor 5 A159A; CC-CKR-5; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine receptor CCR5; chemr13; CMKBR5; HIV-1 fusion coreceptor
CC-CKR-5; CCCKR5; CCR-5; CCR5; CD195; CKR-5; CKR5; CMKBR5; IDDM22