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Abnova
CCRL2 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 2
CCRL2 Antibody (H00009034-B02P) in WB
Western Blot analysis of CCRL2 expression in transfected 293T cell line (H00009034-T02) by CCRL2 MaxPab polyclonal antibody.
Lane 1: CCRL2 transfected lysate(37.84 KDa).
Lane 2: Non-transfected lysate.
Lane 1: CCRL2 transfected lysate(37.84 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00009034-B02P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CCRL2 (NP_003956, 1 a.a. approximately 344 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MANYTLAPED EYDVLIEGEL ESDEAEQCDK YDAQALSAQL VPSLCSAVFV IGVLDNLLVV LILVKYKGLK RVENIYLLNL AVSNLCFLLT LPFWAHAGGD PMCKILIGLY FVGLYSETFF NCLLTVQRYL VFLHKGNFFS ARRRVPCGII TSVLAWVTAI LATLPEFVVY KPQMEDQKYK CAFSRTPFLP ADETFWKHFL TLKMNISVLV LPLFIFTFLY VQMRKTLRFR EQRYSLFKLV FAIMVVFLLM WAPYNIAFFL STFKEHFSLS DCKSSYNLDK SVHITKLIAT THCCINPLLY AFLDGTFSKY LCRCFHLRSN TPLQPRGQSA QGTSREEPDH STEV
Target Information
CCRL2 (C-C chemokine receptor-like 2), also known as chemokine receptor X, human chemokine receptor (HCR), CRAM-A or CRAM-B, is a seven pass transmembrane protein expressed by monocytes, neutrophils, and dendritic cells of immunal tissues (predominanly spleen, fetal liver, bone marrow and lymph node). It shares over 40% homology with other C-C chemokine receptors but does not share the conserved DRY motif which is among the important motifs necessary for signalling and ligand-binding. C-C chemokine receptors are G-protein coupled, seven pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to areas of inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: atypical chemokine receptor 5; C-C chemokine receptor-like 2; chemokine (C-C motif) receptor-like 2; Chemokine receptor CCR11; Chemokine receptor X; MGC116710; Putative MCP-1 chemokine receptor
Gene Aliases: ACKR5; CCR11; CCR6; CCRL2; CKRX; CRAM; CRAM-A; CRAM-B; HCR
UniProt ID: (Human) O00421
Entrez Gene ID: (Human) 9034
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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