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Invitrogen
CD10/CD19 Antibody Cocktail, FITC, PE
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Product Details
MA1-12187
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Cocktail
Type
Antibody
Clone
RXB.14, 1G9
Immunogen
White blood cells.
Conjugate
Form
Liquid
Purification
Protein A/G
Storage buffer
PBS with 0.2% carrier protein
Contains
0.08% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is a monoclonal mixture of FITC-conjugated CD10 (clone RXB.14, isotype IgG1) and PE-conjugated CD19 (clone 1G9, isotype IgG1).
Target Information
Anti-hCD10 recognizes a human common acute lymphoblastic antigen (CALLA), MW 100 kDa. The CD10 antigen is identical to human membrane-associated neutral endopeptidase (NEP;EC 3.3.24.11), also known as enkephalinase. The CD10 antigen is found on lymphocytes from patients with acute B-lymphoid leukemia. The antigen is also present on a wide variety of normal and neoplastic cell types including renal epithellum, fibroblasts, granulocytes and some lymphoma, melanoma and glioma cell lines. Identification of CD19 PE human B cells associated approximately 10% of peripheral blood lymphocytes expressing the 95,000 M.W. surface antigen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Atriopeptidase; AW495831; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; CALLA; CD10; CD19; CD19 differentiation antigen; common acute lymphoblastic leukemia antigen precursor; Common acute lymphocytic leukemia antigen; Differentiation antigen CD19; Enkephalinase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); NEP; NEP-390; NEP-411; Neprilysin; neprilysin-390; neprilysin-411; Neutral endopeptidase 24.11; SFE; Skin fibroblast elastase; T-cell surface antigen Leu-12; unnamed protein product
Gene Aliases: B4; CALLA; CD10; CD19; CMT2T; CVID3; EPN; MME; NEP; SCA43; SFE
UniProt ID: (Human) P15391, (Human) P08473
Entrez Gene ID: (Human) 930, (Human) 4311
phosphatidylserine binding
endopeptidase activity
metallocarboxypeptidase activity
metalloendopeptidase activity
protein binding
peptidase activity
metallopeptidase activity
exopeptidase activity
zinc ion binding
hydrolase activity
peptide binding
protein homodimerization activity
metal ion binding
oligopeptidase activity
cardiolipin binding
B-1 B cell differentiation
adaptive immune response
B cell proliferation involved in immune response
immune system process
immunoglobulin mediated immune response
B cell mediated immunity
B cell proliferation
antigen receptor-mediated signaling pathway
B cell receptor signaling pathway
regulation of B cell receptor signaling pathway
regulation of B cell activation
positive regulation of release of sequestered calcium ion into cytosol
positive regulation of protein kinase B signaling
kidney development
placenta development
angiotensin maturation
proteolysis
peptide metabolic process
learning or memory
substance P catabolic process
bradykinin catabolic process
protein processing
sensory perception of pain
protein catabolic process
lung development
hormone catabolic process
response to estrogen
creatinine metabolic process
beta-amyloid metabolic process
positive regulation of neurogenesis
neuropeptide processing
cellular response to cytokine stimulus
cellular response to UV-A
cellular response to UV-B
replicative senescence
beta-amyloid clearance
amyloid-beta clearance by cellular catabolic process
positive regulation of long-term synaptic potentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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