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      CD105 Monoclonal Antibody (SN6)

      See 37 other CD105 antibodies ›
      CD105 Monoclonal Antibody for Flow

      Catalog#: MHCD10500 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      MHCD10500 0.5 ml
      227.00
      Please enter a quantity in the range of 1 to 199.
      Suggested Secondary Antibodies

      Anti-Mouse Secondary Antibodies (601)
      Alexa Fluor® Anti-Mouse Secondary Antibodies (122)
      HRP Anti-Mouse Secondary Antibodies (86)

      Product Details

      References

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human
      Published species reactivity Human
      Host / Isotype Mouse / IgG1
      Class Monoclonal
      Type Antibody
      Clone SN6
      Immunogen Human CD105 (Endoglin)
      Conjugate Unconjugated
      Form Liquid
      Purification purified
      Storage buffer PBS
      Contains 0.1% sodium azide
      Storage Conditions 4° C, store in dark
      Tested Applications Dilution *
      Flow Cytometry (Flow) Assay-Dependent

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Published Applications
      Immunohistochemistry (IHC) See 1 publications below

      Background/Target Information

      CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

      Analyte Specific Reagent

      References

      Immunohistochemistry

      Species Dilution Title Authors Journal (Vol:Pg) Year
      Human Not Cited Enhancement of Ischemic Wound Healing by Spheroid Grafting of Human Adipose-Derived Stem Cells Treated with Low-Level Light Irradiation.
      MHCD10500 was used in immunohistochemistry to assess the effect of low-level light irradiation prior to transplantation of adipose-derived stromal cell spheroids on a skin wound model       		Park IS,Chung PS,Ahn JC PloS one (10:null) 2015

      Bioinformatics

      Protein Aliases:

      CD105; CD105 antigen; END; Endoglin; ENG; HHT1; ORW; ORW1

      Gene Aliases:

      END; ENG; HHT1; ORW1

      UniProt ID:

      (Human) P17813

      Entrez Gene ID:

      (Human) 2022

      Molecular Function:

      TGF-beta receptor cytokine receptor receptor

      Function(s) Process(es)

      Documents

      Material safety data sheets (MSDS)

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