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Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
0.5-2 µg/mL | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
5-20 µg/mL | - |
Immunocytochemistry (ICC/IF) |
5-20 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein Cluster Of Differentiation 15. The antigen corresponds to amino acid range 144-389 of the target protein. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.87 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS with 50% glycerol |
Contains |
0.05% ProClin 300 |
Storage conditions |
-20°C |
RRID |
AB_2903527 |
CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-fucosyl-N-acetyl-lactosamine epitope; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; alpha (1,3) fucosyltransferase, myeloid specific; alpha 1,3-fucosyltransferase; Alpha-(1,3)-fucosyltransferase 4; Fuc-TIV; Fucosyltransferase 4; Fucosyltransferase IV; Galactoside 3-L-fucosyltransferase; Lewis x; stage-specific embryonic antigen 1
Gene Aliases: AI451562; CD15; Elft; FAL; FucT-IV; Fut4; LeX; SSEA-1; Ssea1
UniProt ID: (Mouse) Q11127
Entrez Gene ID: (Mouse) 14345
Molecular Function:
glycosyltransferase
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