In direct ELISAs, approximately 40% cross-reactivity with recombinant human (rh) ALCAM is observed, and less than 10% cross-reactivity with rhBCAM, recombinant mouse (rm) OCAM, and rmMAdCAM-1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
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Protein Aliases: Activated leukocyte cell adhesion molecule; ALCAM; BEN; CD166; CD166 antigen; cell adhesion molecule; FLJ38514; HB2; KG-CAM; MGC71733; Protein DM-GRASP; Protein MEMD; SB-10 antigen
Gene Aliases: AI853494; Alcam; BEN; CD166; DM-GRASP; MuSC; SC1