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Invitrogen
CD263 (TRAIL-R3) Polyclonal Antibody
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Product Details
PA1-29165
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from the N-terminal extracellular domain of human DcR1 precursor protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
500 µg
Purification
Protein A
Storage buffer
PBS with 0.2% BSA
Contains
0.1% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: Placenta
Target Information
TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antagonist decoy receptor for TRAIL/Apo-2L; cytotoxic TRAIL receptor-3; decoy receptor 1; decoy TRAIL receptor without death domain; DR4 homolog; lymphocyte inhibitor of TRAIL; MGC149501; MGC149502; TNF receptor family member; lacks a cytoplasmic domain; TNF-related apoptosis-inducing ligand receptor 3; TNFR family member; TNFRSF10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; unnamed protein product
Gene Aliases: CD263; DCR1; DCR1-TNFR; LIT; TRAIL-R3; TRAILR3; TRID
UniProt ID: (Human) O14798
Entrez Gene ID: (Human) 8794
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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