This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
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Protein Aliases: CD2 (cytoplasmic tail) binding protein 2; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; protein phosphatase 1, regulatory subunit 59; U5 snRNP 52K protein; U5-52K
Gene Aliases: CD2BP2; FWP010; KIAA1178; LIN1; PPP1R59; Snu40; U5-52K
UniProt ID: (Human) O95400
Entrez Gene ID: (Human) 10421