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Invitrogen
CD32b Polyclonal Antibody
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FIGURE: 1 / 1
CD32b Antibody (PA5-86930) in WB
Western blot analysis of Carbonic Anhydrase IV in Lane 1: PC12 whole cell lysate (40 µg), Lane 2: SP2/0 whole cell lysate (40 µg), Lane 3: THP-1 whole cell lysate (40 µg), Lane 4: MCF-7 whole cell lysate (40 µg). Sample was incubated with Carbonic Anhydrase IV polyclonal antibody (Product # PA5-86930) using a 1:500 dilution.
Product Details
PA5-86930
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide, corresponding to amino acids 250-300 of Human FCGR2B.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD32; CD32 receptor 2; CD32 receptor 2a; CD32 receptor 2b; CD32A; CDw32; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma receptor IIB; Fc gamma RIIB; Fc receptor, IgG, low affinity IIb; FC-gamma RII; fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma-RII; fc-gamma-RIIa; Fc-gamma-RIIb; FcgammaRIIB; FcGR; FCGR2A1; FcRII; fcRII-a; fcRII-b; FGFR2B; IgG Fc receptor II beta; IgG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II; Low affinity immunoglobulin gamma Fc region receptor II-b; Ly-17; Lymphocyte antigen 17
Gene Aliases: AI528646; CD32; CD32B; F630109E10Rik; Fc[g]RII; FCG2; FcgammaRIIB2; FCGR2; Fcgr2a; FCGR2B; FcgRII; Fcr-2; Fcr-3; FCRII; IGFR2; Ly-17; Ly-m20; LyM-1
UniProt ID: (Human) P31994, (Rat) Q63203, (Mouse) P08101
Entrez Gene ID: (Human) 2213, (Rat) 289211, (Mouse) 14130
immune response
signal transduction
viral process
regulation of immune response
negative regulation of type I hypersensitivity
immune complex clearance
negative regulation of immunoglobulin production
negative regulation of inflammatory response to antigenic stimulus
negative regulation of acute inflammatory response to antigenic stimulus
negative regulation of humoral immune response mediated by circulating immunoglobulin
receptor-mediated endocytosis
phagocytosis, engulfment
defense response
cell surface receptor signaling pathway
response to bacterium
immunoglobulin mediated immune response
antigen processing and presentation of exogenous peptide antigen via MHC class II
negative regulation of B cell proliferation
response to estradiol
endocytic recycling
negative regulation of interleukin-10 production
negative regulation of neutrophil apoptotic process
mast cell activation
negative regulation of phagocytosis
positive regulation of phagocytosis
negative regulation of immune response
cellular response to molecule of bacterial origin
cellular response to lipopolysaccharide
intracellular signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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