|Tested species reactivity||Human|
|Published species reactivity||Mouse, Human|
|Host / Isotype||Mouse / IgG2a|
|Storage buffer||PBS with 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 2 publications below|
Our Pacific Blue™ dye is optimally excited by the violet laser and conjugates of this dye are strongly fluorescent even at neutral pH. Pacific Blue™ and Pacific Orange™ dye conjugates can be simultaneously excited at 405 nm and emit at 455 nm and 551 nm, respectively, facilitating two-color analysis.
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Analyte Specific Reagent
Long term maintenance of myeloid leukemic stem cells cultured with unrelated human mesenchymal stromal cells.
MHCD0328 was used in flow cytometry and immunohistochemistry - frozen section to test if mesenchymal stromal cells support the growth and survival of leukemic stem cells in vitro
|Ito S,Barrett AJ,Dutra A,Pak E,Miner S,Keyvanfar K,Hensel NF,Rezvani K,Muranski P,Liu P,Melenhorst JJ,Larochelle A||Stem cell research (14:95)||2015|
Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized mice.
MHCD0328 was used in flow cytometry to examine the effect of lytic EBV antigen-specific CD8+ T cells on EBV infection in humanized mice
|Antsiferova O,Müller A,Rämer PC,Chijioke O,Chatterjee B,Raykova A,Planas R,Sospedra M,Shumilov A,Tsai MH,Delecluse HJ,Münz C||PLoS pathogens (10:null)||2014|