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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Storage buffer||PBS with 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
Our Pacific Blue™ dye is optimally excited by the violet laser and conjugates of this dye are strongly fluorescent even at neutral pH. Pacific Blue™ and Pacific Orange™ dye conjugates can be simultaneously excited at 405 nm and emit at 455 nm and 551 nm, respectively, facilitating two-color analysis.
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Analyte Specific Reagent
Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized mice.
MHCD0328 was used in flow cytometry to examine the effect of lytic EBV antigen-specific CD8+ T cells on EBV infection in humanized mice
|Antsiferova O,Müller A,Rämer PC,Chijioke O,Chatterjee B,Raykova A,Planas R,Sospedra M,Shumilov A,Tsai MH,Delecluse HJ,Münz C||PLoS pathogens (10:null)||2014|
CD3 antigen; CD3 antigen, delta subunit; CD3 delta; CD3-DELTA; CD3/TCR complex; CD3d; CD3d antigen; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule, delta (CD3-TCR complex); delta chain; delta polypeptide TiT3 complex; delta subunit; OKT3; OKT3, delta chain; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 delta chain; T3D
CD3-DELTA; CD3D; IMD19; T3D