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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||PBS with 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Analyte Specific Reagent
Case study interpretation: Report from the ICCS Annual Meeting, Seattle, 2014.
MHCD4101 was used in flow cytometry to discuss how to diagnosis hematolymphoid neoplasms using flow cytometry.
|Fromm JR,Tagliente DJ,Shaver AC,Neppalli V,Craig FE||Cytometry. Part B, Clinical cytometry (88:413)||2015|
GPalpha IIb, alphaIIb protein, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb of IIb/IIIa complex, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, protein phosphatase 1, regulatory subunit 93, BDPLT2, CD41, CD41B, GP2B, GPIIb, GTA, HPA3, integrin alpha-IIb, platelet fibrinogen receptor, alpha subunit, ITGA2B
CD41, BDPLT16, GPIIb, GTA, GP2B, CD41B, HPA3, GT, PPP1R93, BDPLT2