|Tested species reactivity||Human|
|Published species reactivity||Human, Mouse, Not Applicable|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Human IL-2 dependent T cells|
|Storage buffer||PBS with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||20 ul/10^6 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
CD45R0 is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45R0 is expressed e.g. on macrophages, CD8+ T cells, activated T cells and myeloma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A giant primary sclerosing lipogranuloma of the scrotum.
MA1-10235 was used in immunohistochemistry to report on a case of giant primary sclerosing lipogranuloma of the scrotum
|Mungan S,Karagüzel E,Turan C,Re¿s A||Turk patoloji dergisi (30:78)||2014|
Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret.
MA1-10235 was used in immunohistochemistry to study the role of Ret in the neurturin-mediated formation of precise axonal projections in the central nervous system
|Honma Y,Kawano M,Kohsaka S,Ogawa M||Development (Cambridge, England) (137:2319)||2010|
Hyperplasia of hair follicles and other adnexal structures in cutaneous lymphoproliferative disorders: a study of 53 cases, including so-called pseudolymphomatous folliculitis and overt lymphomas.
MA1-10235 was used in immunohistochemistry to study 53 cases of cutaneous lymphoproliferative disorders
|Kazakov DV,Belousova IE,Kacerovska D,Sima R,Vanecek T,Vazmitel M,Pizinger K,Michal M||The American journal of surgical pathology (32:1468)||2008|
A patient with clinicopathologic features of small plaque parapsoriasis presenting later with plaque-stage mycosis fungoides: report of a case and comparative retrospective study of 27 cases of "nonprogressive" small plaque parapsoriasis.
MA1-10235 was used in immunohistochemistry to report on a case of small plaque parapsoriasis with plaque-stage mycosis fungoides
|Belousova IE,Vanecek T,Samtsov AV,Michal M,Kazakov DV||Journal of the American Academy of Dermatology (59:474)||2008|
Primary cutaneous histiocyte and neutrophil-rich CD30+ and CD56+ anaplastic large-cell lymphoma with prominent angioinvasion and nerve involvement in the forehead and scalp of an immunocompetent woman.
MA1-10235 was used in immunohistochemistry to report on a case of utaneous lymphoma of the head co-expressing CD56 and CD30
|Boudova L,Kazakov DV,Jindra P,Sima R,Vanecek T,Kuntscher V,Vera V,Bouda J,Michal M||Journal of cutaneous pathology (33:584)||2006|
Cutaneous lymphoid hyperplasia and other lymphoid infiltrates of the breast nipple: a retrospective clinicopathologic study of fifty-six patients.
MA1-10235 was used in immunohistochemistry to study the clinicopathological spectrum of lymphoproliferations and other lymphoid infiltration of the breast nipple
|Boudova L,Kazakov DV,Sima R,Vanecek T,Torlakovic E,Lamovec J,Kutzner H,Szepe P,Plank L,Bouda J,Hes O,Mukensnabl P,Michal M||The American Journal of dermatopathology (27:375)||2005|
T-cell-rich B-cell lymphoma: a clinicopathologic study of 21 cases and comparison with 43 cases of diffuse large B-cell lymphoma.
MA1-10235 was used in immunohistochemistry to compare the clinocopathology of T-cell rich B-cell lymphoma and diffuse large B-cell lymphoma
|Aki H,Tuzuner N,Ongoren S,Baslar Z,Soysal T,Ferhanoglu B,Sahinler I,Aydin Y,Ulku B,Aktuglu G||Leukemia research (28:229)||2004|
|Not Applicable||Not Cited||
Natural regulatory T cells: number and function are normal in the majority of patients with lupus nephritis.
MA1-10235 was used in flow cytometry to examine the frequency, phenotype, and function of T regulatory cells in patients with systemic lupus erythematosus and inactive disease
|Yates J,Whittington A,Mitchell P,Lechler RI,Lightstone L,Lombardi G||Clinical and experimental immunology (153:44)||2008|
Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers.
MA1-10235 was used in immunocytochemistry to investigate the expression of carboxyl-terminal hydrolyase L1 gene in human airway epithelium of cigarette smokers
|Carolan BJ,Heguy A,Harvey BG,Leopold PL,Ferris B,Crystal RG||Cancer research (66:10729)||2006|
Interferon-alpha and -beta inhibit the in vitro differentiation of immunocompetent human dendritic cells from CD14(+) precursors.
MA1-10235 was used in flow cytometry to test if type-I interferons influence dendritic cell differentiation and function.
|McRae BL,Nagai T,Semnani RT,van Seventer JM,van Seventer GA||Blood (96:210)||2000|