|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Rabbit|
|Immunogen||Synthetic peptide from the intracellular region of CD5|
|Storage buffer||tissue culture supernatant|
|Contains||15mM sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:2|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||2-4 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 7 publications below|
MA5-14560 targets CD5 in IHC (P), FACS and WB applications and shows reactivity with Human samples.
The MA5-14560 immunogen is synthetic peptide from the intracellular region of CD5.
CD5, a transmembrane protein, is found on 95%of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Occasionally, CD5 antigen is also expressed on a subset of B cells. Mantle cell lymphomas (same as diffuse centrocytic lymphomas) are CD5+ while the follicle center cell lymphoma are CD5-.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Increased utilization, verification, and clinical implications of immunocytochemistry: Experience in a northern New England hospital.
MA5-14560 was used in immunohistochemistry to study a northern New England hospital and increased utilization, verification, and clinical implications of immunocytochemistry
|Sauter JL,Ambaye AB,Mount SL||Diagnostic cytopathology (43:688)||2015|
Histopathological, immunophenotypic and clinical particularities and evolution of a case of hepatosplenic T-cell lymphoma in transformation to leukemia.
MA5-14560 was used in immunohistochemistry to report on a case of hepatosplenic T-cell lymphoma with leukemic transformation
|Benedek Lázár E,Köpeczi JB,Tunyogi AB,Kakucs E,Horváth E,Turcu M,Benedek I||Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie (54:1135)||2014|
Primary pure squamous cell carcinoma of the thyroid: report and histogenic consideration of a case involving a BRAF mutation.
MA5-14560 was used in immunohistochemistry to study a case of primary squamous cell carcinoma of the thyroid
|Ko YS,Hwang TS,Han HS,Lim SD,Kim WS,Oh SY||Pathology international (62:43)||2012|
Secondary involvement of the breast in T-cell non-Hodgkin lymphoma, an unusual example mimicking inflammatory breast carcinoma.
MA5-14560 was used in immunohistochemistry to report a clinical case of T-cell non-Hodgkin lymphoma with unusual inflammatory breast carcinoma similarity
|Kelten C,Kabukcu S,Sen N,Teke Z,Yaren A,Erdem E,Duzcan E||Archives of gynecology and obstetrics (280:149)||2009|
Mucoepidermoid thymic carcinoma: a challenging mediastinal aspirate.
MA5-14560 was used in immunohistochemistry to report on a case of mucoepidermoid thymic carcinoma.
|Kapila K,Pathan SK,Amir T,Joneja M,Hebbar S,Al-Ayadhy B||Diagnostic cytopathology (37:433)||2009|
The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry.
MA5-14560 was used in immunohistochemistry to evaluate novel immunohistochemistry reagents and techniques
|Wong SC,Chan JK,Lo ES,Chan AK,Wong MC,Chan CM,Lam MY,Chan AT||Archives of pathology and laboratory medicine (131:1047)||2007|
Clinicopathologic and genetic profile of intracranial marginal zone lymphoma: a primary low-grade CNS lymphoma that mimics meningioma.
MA5-14560 was used in immunohistochemistry to study the clinicopathologic and genetic profile of intracranial marginal zone lymphoma
|Tu PH,Giannini C,Judkins AR,Schwalb JM,Burack R,O'Neill BP,Yachnis AT,Burger PC,Scheithauer BW,Perry A||Journal of clinical oncology : official journal of the American Society of Clinical Oncology (23:5718)||2005|