Top: Lineagelo C57BL/6 bone marrow cells were stained with Anti-Mouse Ly-6A/E (Sca-1) PE and 0.5 µg of Anti-Mouse CD84 APC. Bottom: Staining of mouse splenocytes with 0.5 µg of Armenian Hamster IgG Isotype Control APC (blue histogram) or 0.5 µg of Anti-Mouse CD84 APC (purple histogram, A16412). Total viable cells were used for analysis.
|Tested species reactivity||Mouse|
|Host / Isotype||Armenian hamster / IgG1|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
CD84 is expressed on mature B cells and on B cell lines, including pre B cell lines, but not on plasma cell lines. Immunohistochemical studies demonstrated that CD84 strongly expressed on tissues macrophages. CD84 is also highly expressed on platelets and, at low levels on peripheral blood T cells. It is a highly glycosylated protein and belongs to immunoglobulin superfamily. It may play a role in leukocyte activation.
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