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          • Primary Antibodies ›
          • CDC14B Antibodies

          Proteintech

          CDC14B Polyclonal Antibody

          1 Reference
          View all (6) CDC14B antibodies

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          Cite CDC14B Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          CDC14B Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          CDC14B Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          CDC14B Antibody (25187-1-AP) in WB

          SMMC-7721 cells were subjected to SDS PAGE followed by western blot with 25187-1-AP ( CDC14B Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CDC14B Antibody in Western Blot (WB)
          CDC14B Polyclonal Antibody

          Product Details

          25187-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:200-1:1,000
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          CDC14B Fusion Protein Ag18227 (349-498 aa encoded by BC156666)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.33 mg/mL

          Amount

          49.5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: PGSVIGPQQ QFLVMKQTNL WLEGDYFRQK LKGQENGQHR AAFSKLLSGV DDISINGVEN QDQQEPEPYS DDDEINGVTQ GDRLRALKSR RQSKTNAIPL TVILQSSVQS CKTSEPNISG SAGITKRTTR SASRKSSVKS LSISRTKTVL R (349-498 aa encoded by BC156666)

          Target Information

          CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CDC14 cell division cycle 14 homolog B; CDC14B; similar to Saccharomyces cerevisiae Cdc14p; CDC14Bpar; dual specific protein; Dual specificity protein phosphatase CDC14B; unnamed protein product

          View more View less

          Gene Aliases: CDC14B; Cdc14B1; Cdc14B2; CDC14B3; hCDC14B

          View more View less

          UniProt ID: (Human) O60729

          View more View less

          Entrez Gene ID: (Human) 8555

          View more View less

          Function(s)
          phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein binding hydrolase activity
          Process(es)
          microtubule cytoskeleton organization DNA repair protein dephosphorylation cellular response to DNA damage stimulus mitotic G2 DNA damage checkpoint regulation of exit from mitosis positive regulation of cytokinesis cilium morphogenesis positive regulation of ubiquitin protein ligase activity
          It has to be done as per old AB suggested Products section.

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