|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 184 and 397 of Human CDCA7L|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31761 targets CDCA7L in WB applications and shows reactivity with Human samples.
The PA5-31761 immunogen is recombinant fragment corresponding to a region within amino acids 184 and 397 of Human CDCA7L.
Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cell division cycle associated 7-like; Cell division cycle-associated 7-like protein; JPO2; Protein JPO2; R1; RAM2; Transcription factor RAM2
Gene Aliases: CDCA7L; HR1; JPO2; R1; RAM2
UniProt ID: (Human) Q96GN5
Entrez Gene ID: (Human) 55536
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