In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Orangutan, Monkey (95%) Marmoset (84%).
This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described.
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Protein Aliases: Cadherin; Cadherin-related family member 5; differentiation-associated catenin regulator; MLPCDH; Mu-protocadherin; Mucin and cadherin-like protein; Mucin-like protocadherin
Gene Aliases: CDHR5; MLPCDH; MU-PCDH; MUCDHL; MUPCDH; UNQ2781/PRO7168
UniProt ID: (Human) Q9HBB8
Entrez Gene ID: (Human) 53841
Molecular Function: cadherin