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Proteintech
CDK5RAP1 Polyclonal Antibody
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Product Details
14740-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CDK5RAP1 Fusion Protein Ag6409 (239-587 aa encoded by BC050706)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Amount
28.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPVQTSASA TSAFVSIMRG CDNMCSYCIV PFTRGRERSR PIASILEEVK KLSEQGLKEV TLLGQNVNSF RDNSEVQFNS AVPTNLSRGF TTNYKTKQGG LRFAHLLDQV SRVDPEMRIR FTSPHPKDFP DEVLQLIHER DNICKQIHLP AQSGSSRVLE AMRRGYSREA YVELVHHIRE SIPGVSLSSD FIAGFCGETE EDHVQTVSLL REVQYNMGFL FAYSMRQKTR AYHRLKDDVP EEVKLRRLEE LITIFREEAT KANQTSVGCT QLVLVEGLSK RSATDLCGRN DGNLKVIFPD AEMEDVNNPG LRVRAQPGDY VLVKITSASS QTLRGHVLCR TTLRDSSAYC (239-587 aa encoded by BC050706)
Target Information
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. Multiple transcript variants exist for this gene, but the full-length natures of only two have been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDK5 activator-binding protein C42; CDK5 regulatory subunit associated protein 1; CDK5 regulatory subunit-associated protein 1; CDK5RAP1.3; CDK5RAP1.4; Mitochondrial tRNA methylthiotransferase CDK5RAP1; mt-tRNA-2-methylthio-N6-dimethylallyladenosine synthase; mt-tRNA-N6-(dimethylallyl)adenosine(37) methylthiotransferase; unnamed protein product
Gene Aliases: 2310066P17Rik; C20orf34; C42; CDK5RAP1; CGI-05; HSPC167
UniProt ID: (Human) Q96SZ6, (Rat) Q9JLH6, (Mouse) Q8BTW8
Entrez Gene ID: (Human) 51654, (Rat) 252827, (Mouse) 66971
regulation of cyclin-dependent protein serine/threonine kinase activity
tRNA modification
brain development
cell proliferation
regulation of neuron differentiation
negative regulation of cyclin-dependent protein serine/threonine kinase activity
regulation of protein kinase activity
tRNA processing
RNA modification
tRNA methylthiolation
negative regulation of cell cycle
positive regulation of translational fidelity
regulation of protein metabolic process
positive regulation of mitochondrial translation
mitochondrial tRNA modification
macromolecule modification
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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