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Product Details
16615-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CDKN2AIP Fusion Protein Ag9907 (230-579 aa encoded by BC022270)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: ASEAEAPDK HGSSFVSLLK SSVNSHMTQS TDSRQQSGSP KKSALEGSSA SASQSSSEIE VPLLGSSGSS EVELPLLSSK PSSETASSGL TSKTSSEASV SSSVAKNSSS SGTSLLTPKS SSSTNTSLLT SKSTSQVAAS LLASKSSSQT SGSLVSKSTS LASVSQLASK SSSQTSTSQL PSKSTSQSSE SSVKFSCKLT NEDVKQKQPF FNRLYKTVAW KLVAVGGFSP NVNHGELLNA AIEALKATLD VFFVPLKELA DLPQNKSSQE SIVCELRCKS VYLGTGCGKS KENAKAVASR EALKLFLKKK VVVKICKRKY RGSEIEDLVL LDEESRPVNL PPALKHPQEL L (230-579 aa encoded by BC022270)
Target Information
CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CDKN2A-interacting protein; collaborates/cooperates with ARF (alternate reading frame) protein; Collaborator of ARF
Gene Aliases: 4921511I16Rik; AW208986; CARF; CDKN2AIP; RGD1305302
UniProt ID: (Human) Q9NXV6, (Mouse) Q8BI72, (Rat) Q5U2X0
Entrez Gene ID: (Human) 55602, (Mouse) 70925, (Rat) 306455
Molecular Function:
DNA-binding transcription factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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