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CDKN2D Polyclonal Antibody
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Product Details
BS-5982R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CDKN2D/p19 INK4d, amino acids 65-166.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
p19 is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDK inhibitor p19INK4d; CDK4I; CDKN2D; cell cycle inhibitor, Nur77 associating protein; Cyclin-dependent kinase 4 inhibitor D; cyclin-dependent kinase 4 inhibitor D p19; cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4); inhibitor of cyclin-dependent kinase 4d; MTS1; p16-INK4; p16-INK4a; p19-INK4d
Gene Aliases: CDKN2D; INK4D; p19; p19-INK4D; p19INK4d
UniProt ID: (Human) P55273, (Mouse) Q60773
Entrez Gene ID: (Human) 1032, (Rat) 494444, (Mouse) 12581
DNA synthesis involved in DNA repair
sensory perception of sound
negative regulation of cell proliferation
response to UV
negative regulation of cell growth
response to retinoic acid
response to vitamin D
autophagic cell death
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
regulation of cell cycle G1/S phase transition
negative regulation of cell cycle G1/S phase transition
regulation of G1/S transition of mitotic cell cycle
negative regulation of G1/S transition of mitotic cell cycle
regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
cell cycle
cell cycle arrest
negative regulation of phosphorylation
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of protein serine/threonine kinase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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