PA1-24393 detects CDX2 in Human samples.
PA1-24393 has been successfully used in Western Blot procedures.
PA1-24393 immunogen corresponds to Polyclonal antibody from rabbits immunized with a synthetic peptide region of human CDX2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
CDX2 is a member of caudal type homeo box family of transcription factor. CDX-2 is a permissive factor that influences basal CaBP expression in enterocytes; HNF-1alpha; modulates CaBP gene expression during cellular differentiation. CDX2, but not CDX1, interacts with the MUC2 promoter and activates MUC2 transcription, and plays an important role in the differentiation of goblet cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: caudal type homeo box transcription factor 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX-3; CDX3; Homeobox protein CDX-2; homeobox protein miniCDX2
Gene Aliases: CDX-3; CDX2; CDX2/AS; CDX3
UniProt ID: (Human) Q99626
Entrez Gene ID: (Human) 1045