Recommended positive controls: A431, H1299, HeLaS3.
Predicted reactivity: Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.
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Protein Aliases: CDY-like; CDY-like, autosomal; Chromodomain Y-like protein; Crotonyl-CoA hydratase; DKFZp586C1622; MGC131936; testis-specific chromodomain Y-like protein
Gene Aliases: CDYL; CDYL1
UniProt ID: (Human) Q9Y232
Entrez Gene ID: (Human) 9425