Peptide sequence: YIHDFNRRHT EKQKESTLTR TNRTSPNNAR KQISRSTNSN FSKTSPKALV
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 86%
Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDY-like; CDY-like, autosomal; CDYL1; Chromodomain protein; chromodomain protein Y-like variant 2; chromodomain protein Y-like variant 3; chromodomain protein Y-like variant 4; chromodomain protein, Y chromosome-like; chromodomain protein, Y-like; Chromodomain Y-like protein; Crotonyl-CoA hydratase; DKFZP586C1622; MGC131936; Putative histone acetyltransferase Cdyl; Putative tubulin acetyltransferase Cdyl; testis-specific chromodomain Y-like protein; Y-like
Gene Aliases: AI325931; BOS_22064; CDYL; CDYL1