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Invitrogen
CEACAM3 Polyclonal Antibody
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FIGURE: 1 / 1
CEACAM3 Antibody (PA5-96177) in WB
Western blot analysis of CEACAM3 in A549 cells. Samples were incubated with CEACAM3 Polyclonal antibody (Product # PA5-96177) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-96177
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human CD66d/CEACAM3 (NP_0018062)
Conjugate
Form
Liquid
Concentration
1.71 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MGPPSASPHR ECIPWQGLLL TASLLNFWNP PTTAKLTIES MPLSVAEGKE VLLLVHNLPQ HLFGYSWYKG ERVDGNSLIV GYVIGTQQAT PGAAYSGRET IYTNASLLIQ NVTQNDIGFY TLQVIKSDLV NEEAT; Positive Samples: A-549, Mouse spleen; Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Carcinoembryonic antigen CGM1; carcinoembryonic antigen gene family member 1; Carcinoembryonic antigen-related cell adhesion molecule 3; CD66d; CD66d antigen; CEA cell adhesion molecule 3; Cell adhesion molecule CEACAM3; nonspecific cross-reacting antigen; pregnancy-specific glycoprotein 24
Gene Aliases: CD66D; CEA; cea12; CEACAM3; CGM1; EG384557; Psg24; W264; W282
UniProt ID: (Human) P40198
Entrez Gene ID: (Human) 1084, (Mouse) 384557
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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