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Proteintech
CEP164 Polyclonal Antibody
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Product Details
22227-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CEP164 Fusion Protein Ag17570 (1-112 aa encoded by BC000602)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Amount
43.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAGRPLRIG DQLVLEEDYD ETYIPSEQEI LEFAREIGID PIKEPELMWL AREGIVAPLP GEWKPCQDIT GDIYYFNFAN GQSMWDHPCD EHYRSLVIQE RAKLSTSGAI KKK (1-112 aa encoded by BC000602)
Target Information
CEP164 was initially identified as a centrosomal protein, but other studies have indicated that it also plays a role in the formation of primary cilia, the microtubule-based sensory antennae projecting from the surface of many eukaryotic cells as well as in DNA damage response acting as a mediator protein. CEP164 interacts with both ATR and ATM, proteins that trigger a number of cellular responses including the initiation of DNA damaged-induced cell cycle checkpoints. It is phosphorylated upon replication stress, ultraviolet (UV) radiation, and ionizing radiation silencing of CEP164 significantly reduces the DNA damage-induced phosphorylation of several proteins in the DNA damage-activated signaling cascade and compromises cell survival after UV damage. At least two isoforms of CEP164 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ce164; centrosomal protein 164kDa; Centrosomal protein of 164 kDa; Cep 164; Cep164; unnamed protein product
Gene Aliases: CEP164; KIAA1052; NPHP15
UniProt ID: (Human) Q9UPV0
Entrez Gene ID: (Dog) 489389, (Human) 22897
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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