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Invitrogen
CEP41 Polyclonal Antibody
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FIGURE: 1 / 2
CEP41 Antibody (PA5-103727) in ICC/IF
Immunocytochemistry analysis of CEP41 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with CEP41 polyclonal antibody (Product # PA5-103727) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-103727
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CEP41(Accession Q9BYV8), corresponding to amino acid residues D182-A232.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CEP41.
Target Information
Centrosomes are the major microtubule-organizing centers of mammalian cells. They are composed of a centriole pair and surrounding microtubule-nucleating material termed pericentriolar material (PCM). Bipolar mitotic spindle assembly relies on two intertwined processes: centriole duplication and centrosome maturation. Failure to properly orchestrate centrosome duplication and maturation is subsequently linked to spindle defects, which can result in aneuploidy and promote cancer progression. The CEP41 (centrosomal protein of 41 kDa) gene encodes a protein of 373 amino acids that is alternatively spliced into 4 isoforms. Isoforms 1 and 4 are expressed in testis, as well as in and fetal brain and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: centrosomal protein 41 kDa; centrosomal protein 41kDa; Centrosomal protein of 41 kDa; Cep41; testis specific gene A14; testis specific protein A14; testis specific, 14; Testis-specific gene A14 protein
Gene Aliases: 1700017E11Rik; 2810431D15Rik; CEP41; JBTS15; TSGA14
UniProt ID: (Human) Q9BYV8, (Mouse) Q99NF3, (Rat) Q4KM37
Entrez Gene ID: (Human) 95681, (Mouse) 83922, (Rat) 500069
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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