In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human Cerberus is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein antagonists that can bind directly to BMPs and inhibit their activity.
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Protein Aliases: Cer-l; Cerberus; cerberus homolog; Cerberus-like protein; Cerberus-related protein; MGC119894; MGC119895; MGC96951
Gene Aliases: cer-1; Cer1; Cerl; Cerl1; Cerr1
UniProt ID: (Mouse) O55233
Entrez Gene ID: (Mouse) 12622