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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CHML Antibodies

          Invitrogen

          CHML Polyclonal Antibody

          View all (9) CHML antibodies

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          Cite CHML Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          CHML Antibody in Immunocytochemistry (ICC/IF)
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          CHML Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          CHML Antibody (PA5-83093) in ICC/IF

          Immunofluorecent analysis of CHML in human cell line PC-3 using CHML Polyclonal Antibody (Product # PA5-83093). Staining shows localization to nucleus and cytosol. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CHML Antibody in Immunocytochemistry (ICC/IF)
          CHML Antibody in Western Blot (WB)
          CHML Polyclonal Antibody

          Product Details

          PA5-83093

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human CHML. Recombinant protein control fragment (Product #RP-104599).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2790249

          Product Specific Information

          Immunogen sequence: VEESVEKEKY CGDKTCMHTV SDKDGDKDES KSTVEDKADE PIRNRITYSQ IVKEGRRFNI DLVS

          Highest antigen sequence indentity to the following orthologs: Mouse - 70%, Rat - 38%.

          Target Information

          Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction. The component A may be regenerated by transferring its prenylated Rab to a protein acceptor. Less effective than REP-1 in supporting prenylation of Rab3 family.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: choroideraemia-like protein; choroideremia-like (Rab escort protein 2); Choroideremia-like protein; Rab escort protein 2; Rab proteins geranylgeranyltransferase component A 2; REP-2

          View more View less

          Gene Aliases: CHML; REP2

          View more View less

          UniProt ID: (Human) P26374

          View more View less

          Entrez Gene ID: (Human) 1122

          View more View less

          Function(s)
          GDP-dissociation inhibitor activity GTPase activator activity oxidoreductase activity Rab GTPase binding G-protein modulator protein-binding activity modulator
          Process(es)
          intracellular protein transport small GTPase mediated signal transduction protein geranylgeranylation positive regulation of GTPase activity oxidation-reduction process
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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