This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: MSKLGKFFKG GGSSKSRAAP SPQEALVRLR ETEEMLGKKQ EYLENRIQRE IALAKKHGTQ N
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.
CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Charged multivesicular body protein 4c; CHMP4c; chromatin modifying protein 4C; Chromatin-modifying protein 4c; hSnf7-3; hVps32-3; Shax3; SNF7 homolog associated with Alix 3; Snf7 homologue associated with Alix 3; SNF7-3; Vacuolar protein sorting-associated protein 32-3; Vps32-3; VPS32C
Gene Aliases: CHMP4C; SHAX3; SNF7-3; VPS32C
UniProt ID: (Human) Q96CF2
Entrez Gene ID: (Human) 92421
Molecular Function: transfer/carrier protein