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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human CHRM4.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Percent identity with other species by BLAST analysis: Human, Gorilla, Mouse, Rat, Bovine, Hamster, Horse, Pig, Guinea pig (100%) Dog, Elephant, Panda (95%) Bat (90%).
Muscarinic acetylcholine receptor M4 is an Acetylcholine Receptor. Unlike muscarinic receptor M2, the M4 receptor is not involved in smooth muscle contraction. The clinical relevance of this receptor is unknown. However, mouse studies have linked it to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. ESTs have been isolated from human breast and eye libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
acetylcholine receptor, muscarinic 4; cholinergic receptor, muscarinic 4; CHRM4; HM4; M4 muscarinic receptor; M4R; Muscarinic m4 receptor; Muscarinic receptor m4
CHRM4; HM4; M4R