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Bioss
CHRNB Polyclonal Antibody
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Product Details
BS-4247R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CHRNB2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor beta 2 neural; Acetylcholine receptor beta 4; acetylcholine receptor, nicotinic, beta 2 (neuronal); acetylcholine receptor, nicotinic, beta 4 (neuronal); beta2 human neuronal nicotinic acetylcholine receptor; cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic beta 4; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta 4 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 4; cholinergic receptor, nicotinic, beta subunit 2; N-alpha 1; N-alpha 2; Neuronal acetylcholine receptor non-alpha-1 chain; Neuronal acetylcholine receptor non-alpha-2 chain; Neuronal acetylcholine receptor subunit beta-2; Neuronal acetylcholine receptor subunit beta-4; neuronal nicotinic acetylcholine receptor beta 2; neuronal nicotinic receptor beta 4 subunit; nicotinic acetylcholine receptor beta4 subunit
Gene Aliases: [b]2-nAchR; Acrb-2; Acrb-4; Acrb2; Acrb4; C030030P04Rik; CHRNB2; CHRNB4; EFNL3; nAChRB2
UniProt ID: (Human) P17787, (Human) P30926, (Rat) P12390, (Mouse) Q9ERK7, (Mouse) Q8R493, (Rat) P12392
Entrez Gene ID: (Human) 1141, (Human) 1143, (Rat) 54239, (Mouse) 11444, (Mouse) 108015, (Rat) 25103
acetylcholine-activated cation-selective channel activity
protein binding
drug binding
ligand-gated ion channel activity
acetylcholine receptor activity
acetylcholine binding
protein heterodimerization activity
ion channel activity
extracellular ligand-gated ion channel activity
ligand-gated ion channel
action potential
conditioned taste aversion
response to hypoxia
ion transport
calcium ion transport
smooth muscle contraction
signal transduction
synaptic transmission, cholinergic
neuromuscular synaptic transmission
visual perception
sensory perception of sound
learning
memory
locomotory behavior
associative learning
visual learning
regulation of dopamine secretion
sensory perception of pain
vestibulocochlear nerve development
optic nerve morphogenesis
lateral geniculate nucleus development
central nervous system projection neuron axonogenesis
positive regulation of B cell proliferation
regulation of synaptic transmission, dopaminergic
positive regulation of synaptic transmission, dopaminergic
positive regulation of dopamine secretion
response to nicotine
behavioral response to nicotine
social behavior
regulation of dopamine metabolic process
B cell activation
response to cocaine
regulation of circadian sleep/wake cycle, REM sleep
regulation of circadian sleep/wake cycle, non-REM sleep
response to ethanol
negative regulation of action potential
regulation of dendrite morphogenesis
neurological system process
cognition
protein heterooligomerization
membrane depolarization
regulation of synapse assembly
synaptic transmission involved in micturition
cation transmembrane transport
regulation of smooth muscle contraction
regulation of neurotransmitter secretion
positive regulation of transmission of nerve impulse
central nervous system neuron axonogenesis
regulation of membrane potential
transport
cation transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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