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Product Details
22192-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHRNB4 Fusion Protein Ag16767 (332-451 aa encoded by BC096080)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: WVKRCFLHK LPTFLFMKRP GPDSSPARAF PPSKSCVTKP EATATSTSPS NFYGNSMYFV NPASAASKSP AGSTPVAIPR DFWLRSSGRF RQDVQEALEG VSFIAQHMKN DDEDQSVVED W (332-451 aa encoded by BC096080)
Target Information
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor, nicotinic, beta 4 (neuronal); cholinergic receptor; cholinergic receptor, nicotinic beta 4; cholinergic receptor, nicotinic, beta 4 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 4; nAChRB4; Neuronal acetylcholine receptor subunit beta-4; neuronal nicotinic receptor beta 4 subunit; nicotinic acetylcholine receptor beta4 subunit
Gene Aliases: Acrb-4; Acrb4; CHRNB4
UniProt ID: (Human) P30926, (Mouse) Q8R493
Entrez Gene ID: (Human) 1143, (Mouse) 108015
action potential
ion transport
smooth muscle contraction
regulation of smooth muscle contraction
signal transduction
synaptic transmission, cholinergic
locomotory behavior
response to nicotine
behavioral response to nicotine
regulation of neurotransmitter secretion
protein heterooligomerization
positive regulation of transmission of nerve impulse
synaptic transmission involved in micturition
cation transmembrane transport
transport
regulation of membrane potential
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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