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CHST3 Polyclonal Antibody

CHST3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CHST3 Antibody (18242-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human breast cancer using 18242-1-AP (CHST3 antibody) at dilution of 1:100 (under 40x lens).

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Product Details

18242-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CHST3 Fusion Protein Ag13008 (46-479 aa encoded by BC093690)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: SRVSDKLKQ IPQALADANS TDPALILAEN ASLLSLSELD SAFSQLQSRL RNLSLQLGVE PAMEAAGEEE EEQRKEEEPP RPAVAGPRRH VLLMATTRTG SSFVGEFFNQ QGNIFYLFEP LWHIERTVSF EPGGANAAGS ALVYRDVLKQ LFLCDLYVLE HFITPLPEDH LTQFMFRRGS SRSLCEDPVC TPFVKKVFEK YHCKNRRCGP LNVTLAAEAC RRKEHMALKA VRIRQLEFLQ PLAEDPRLDL RVIQLVRDPR AVLASRMVAF AGKYKTWKKW LDDEGQDGLR EEEVQRLRGN CESIRLSAEL GLQQPAWLRG RYMLVRYEDV ARGPLQKARE MYRFAGIPLT PQVEDWIQKN TQAAHDGSGI YSTQKNSSEQ FEKWRFSMPF KLAQVVQAAC GPAMRLFGYK LARDAAALTN RSVSLLEERG TFWVT (46-479 aa encoded by B C093690)

Target Information

CHST3 is an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrixand most cells which is involved in cell migration and differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

N-terminome analyses underscore the prevalence of SPPL3-mediated intramembrane proteolysis among Golgi-resident enzymes and its role in Golgi enzyme secretion.

Cellular and molecular life sciences : CMLS

Hobohm L,Koudelka T,Bahr FH,Truberg J,Kapell S,Schacht SS,Meisinger D,Mengel M,Jochimsen A,Hofmann A,Heintz L,Tholey A,Voss M

Sun Mar 13 00:00:00 UTC 2022

Aging-Associated Changes in Cognition, Expression and Epigenetic Regulation of Chondroitin 6-Sulfotransferase Chst3.

Cells

Baidoe-Ansah D,Sakib S,Jia S,Mirzapourdelavar H,Strackeljan L,Fischer A,Aleshin S,Kaushik R,Dityatev A

Mon Jun 27 00:00:00 UTC 2022

Abnormal expression of chondroitin sulfate sulfotransferases in the articular cartilage of pediatric patients with Kashin-Beck disease.

Histochemistry and cell biology

Lei J,Yan S,Zhou Y,Wang L,Zhang J,Guo X,Lammi MJ,Han J,Qu C

Sun Mar 01 00:00:00 UTC 2020

Serious Selenium Deficiency in the Serum of Patients with Kashin-Beck Disease and the Effect of Nano-Selenium on Their Chondrocytes.

Biological trace element research

Wang L,Yin J,Yang B,Qu C,Lei J,Han J,Guo X

Sun Mar 01 00:00:00 UTC 2020

The effects of long-term low selenium diet on the expression of CHST-3, CHST-12 and UST in knee cartilage of growing rats.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

Wang L,Guo X,Yi J,Qu C,Lei J,Guo Q,Han J

Sat Dec 01 00:00:00 UTC 2018

Altered expression of chondroitin sulfate structure modifying sulfotransferases in the articular cartilage from adult osteoarthritis and Kashin-Beck disease.

Osteoarthritis and cartilage

Han J,Li D,Qu C,Wang D,Wang L,Guo X,Lammi MJ

Tue Aug 01 00:00:00 UTC 2017

Altered expression of chondroitin sulfate structure modifying sulfotransferases in the articular cartilage from adult osteoarthritis and Kashin-Beck disease.

Osteoarthritis and cartilage

Han J,Li D,Qu C,Wang D,Wang L,Guo X,Lammi MJ

Tue Aug 01 00:00:00 UTC 2017

OASIS regulates chondroitin 6-O-sulfotransferase 1 gene transcription in the injured adult mouse cerebral cortex.

Journal of neurochemistry

Okuda H,Tatsumi K,Horii-Hayashi N,Morita S,Okuda-Yamamoto A,Imaizumi K,Wanaka A

Mon Sep 01 00:00:00 UTC 2014

OASIS regulates chondroitin 6-O-sulfotransferase 1 gene transcription in the injured adult mouse cerebral cortex.

Journal of neurochemistry

Okuda H,Tatsumi K,Horii-Hayashi N,Morita S,Okuda-Yamamoto A,Imaizumi K,Wanaka A

Mon Sep 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: C6ST; C6ST-1; carbohydrate (chondroitin 6) sulfotransferase 3; carbohydrate (chondroitin 6/keratan) sulfotransferase 3; Carbohydrate sulfotransferase 3; chondroitin 6 sulfotransferase 1; Chondroitin 6-O-sulfotransferase 1; Chondroitin 6-sulfotransferase; chondroitin 6-sulfotransferase 3; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0; GST; GST-0

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Gene Aliases: C6ST; C6ST-1; C6ST1; CHST3; GST-0; Gst0; HSD

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UniProt ID: (Human) Q7LGC8, (Mouse) O88199, (Rat) Q9QZL2

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Entrez Gene ID: (Human) 9469, (Mouse) 53374, (Rat) 84468

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Function(s)

N-acetylglucosamine 6-O-sulfotransferase activity sulfotransferase activity chondroitin 6-sulfotransferase activity proteoglycan sulfotransferase activity transferase activity transferase

Process(es)

positive regulation of defense response to virus by host carbohydrate metabolic process sulfur compound metabolic process peripheral nervous system axon regeneration chondroitin sulfate biosynthetic process positive regulation of cellular component movement mitophagy in response to mitochondrial depolarization xenophagy T cell homeostasis

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CHST3 Polyclonal Antibody

CHST3 Antibody (18242-1-AP) in IHC (P)

Product Details

18242-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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