Proteintech

CHST3 Polyclonal Antibody

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CHST3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer using 18242-1-AP (CHST3 antibody) at dilution of 1:100 (under 40x lens).

CHST3 Antibody in Western Blot (WB) — Mouse heart tissue were subjected to SDS PAGE followed by western blot with 18242-1-AP (CHST3 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

Product Details

18242-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	-
Immunohistochemistry (IHC)	-	View 2 publications 2 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CHST3 Fusion Protein Ag13008 (46-479 aa encoded by BC093690) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.21 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: SRVSDKLKQ IPQALADANS TDPALILAEN ASLLSLSELD SAFSQLQSRL RNLSLQLGVE PAMEAAGEEE EEQRKEEEPP RPAVAGPRRH VLLMATTRTG SSFVGEFFNQ QGNIFYLFEP LWHIERTVSF EPGGANAAGS ALVYRDVLKQ LFLCDLYVLE HFITPLPEDH LTQFMFRRGS SRSLCEDPVC TPFVKKVFEK YHCKNRRCGP LNVTLAAEAC RRKEHMALKA VRIRQLEFLQ PLAEDPRLDL RVIQLVRDPR AVLASRMVAF AGKYKTWKKW LDDEGQDGLR EEEVQRLRGN CESIRLSAEL GLQQPAWLRG RYMLVRYEDV ARGPLQKARE MYRFAGIPLT PQVEDWIQKN TQAAHDGSGI YSTQKNSSEQ FEKWRFSMPF KLAQVVQAAC GPAMRLFGYK LARDAAALTN RSVSLLEERG TFWVT (46-479 aa encoded by B C093690)

Target Information

CHST3 is an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrixand most cells which is involved in cell migration and differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Altered expression of chondroitin sulfate structure modifying sulfotransferases in the articular cartilage from adult osteoarthritis and Kashin-Beck disease.

Osteoarthritis and cartilage

Han J,Li D,Qu C,Wang D,Wang L,Guo X,Lammi MJ

Tue Aug 01 00:00:00 EDT 2017

OASIS regulates chondroitin 6-O-sulfotransferase 1 gene transcription in the injured adult mouse cerebral cortex.

Journal of neurochemistry

Okuda H,Tatsumi K,Horii-Hayashi N,Morita S,Okuda-Yamamoto A,Imaizumi K,Wanaka A

Mon Sep 01 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: C6ST; C6ST-1; carbohydrate (chondroitin 6) sulfotransferase 3; carbohydrate (chondroitin 6/keratan) sulfotransferase 3; Carbohydrate sulfotransferase 3; chondroitin 6 sulfotransferase 1; Chondroitin 6-O-sulfotransferase 1; Chondroitin 6-sulfotransferase; chondroitin 6-sulfotransferase 3; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0; GST-0

Gene Aliases: C6ST; C6ST-1; C6ST1; CHST3; GST-0; Gst0; HSD

UniProt ID: (Human) Q7LGC8, (Mouse) O88199, (Rat) Q9QZL2

Entrez Gene ID: (Human) 9469, (Mouse) 53374, (Rat) 84468

Molecular Function: transferase