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Product Details
12287-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CIDEC Fusion Protein Ag2913 (1-238 aa encoded by BC016851)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
12287-1-AP recognizing CIDEC (calculated 28 kDa) as a 30 kDa and 45-50 kDa due to its posttranslational modification.
Immunogen sequence: MEYAMKSLS LLYPKSLSRH VSVRTSVVTQ QLLSEPSPKA PRARPCRVST ADRSVRKGIM AYSLEDLLLK VRDTLMLADK PFFLVLEEDG TTVETEEYFQ ALAGDTVFMV LQKGQKWQPP SEQGTRHPLS LSHKPAKKID VARVTFDLYK LNPQDFIGCL NVKATFYDTY SLSYDLHCCG AKRIMKEAFR WALFSMQATG HVLLGTSCYL QQLLDATEEG QPPKGKASSL IPTCLKILQ (1-238 aa encoded by BC016851 )
Target Information
DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF). DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45). Recently a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs. There are 2 transcripts, CIDE-3 and CIDE-3alpha, were present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumours, CIDE-3 may play an important role in prevention of tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cell death activator CIDE-3; cell death-inducing DFFA-like effector c; Cell death-inducing DFFA-like effector protein C; CID; cide 3; fat specific protein 27; Fat-specific protein FSP27 homolog; Lipid transferase CIDEC
Gene Aliases: CIDE-3; CIDE3; CIDEC; FPLD5; FSP27
UniProt ID: (Human) Q96AQ7
Entrez Gene ID: (Human) 63924
Performance Guarantee
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