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Invitrogen
CIDEC Polyclonal Antibody
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Product Details
PA1-46128
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Residues 10-25 of the 27 kDa human FSP27 (CIDE-3) protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Suggested positive control: antigen standard for CIDEC (transient overexpression lysate).
Immunogen sequence: LLYPKSLSRH VSVRTS
Target Information
DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF). DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45). Recently a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs. There are 2 transcripts, CIDE-3 and CIDE-3alpha, were present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumours, CIDE-3 may play an important role in prevention of tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cell death activator CIDE-3; Cell death-inducing DFFA-like effector protein C; CID; cide 3; CIDE-3alpha; fat specific gene 27; fat specific protein 27; Fat-specific protein FSP27; Fat-specific protein FSP27 homolog; Lipid transferase CIDEC; unnamed protein product
Gene Aliases: CIDE-3; CIDE3; CIDEC; FPLD5; FSP27
UniProt ID: (Human) Q96AQ7, (Rat) Q5XI33, (Mouse) P56198
Entrez Gene ID: (Human) 63924, (Rat) 500292, (Mouse) 14311
lipid transport
apoptotic process
lipid storage
lipid particle organization
negative regulation of lipid catabolic process
negative regulation of triglyceride metabolic process
execution phase of apoptosis
intermembrane lipid transfer
lipid droplet fusion
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of apoptotic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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