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CK1 delta Antibody (PA5-106816) in ICC/IF
Immunocytochemistry analysis of CK1 delta in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with CK1 delta polyclonal antibody (Product # PA5-106816) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated g... View More
Product Details
PA5-106816
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CSNK1D(Accession P48730), corresponding to amino acid residues W290-V340.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854481
Product Specific Information
Antibody detects endogenous levels of total Casein Kinase 1 delta.
Target Information
CSNK1D (CK1 delta), a serine/threonine kinase, plays a critical role in Wnt/beta-catenin signaling pathway. This pathway is important in both development and cancer. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for CK1 delta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: casein kinase 1; casein kinase 1, delta; Casein kinase I isoform delta; CK1d; CK1delta; CKI-delta; CKId; HGNC:2452; Tau-protein kinase CSNK1D
Gene Aliases: 1200006A05Rik; AA409348; ASPS; CKIdelta; CSNK1D; D930010H05Rik; FASPS2; HCKID
UniProt ID: (Human) P48730, (Rat) Q06486, (Mouse) Q9DC28
Entrez Gene ID: (Human) 1453, (Rat) 64462, (Mouse) 104318
glycoprotein binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
peptide binding
tau-protein kinase activity
phosphoprotein binding
cadherin binding involved in cell-cell adhesion
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
G2/M transition of mitotic cell cycle
positive regulation of protein phosphorylation
DNA repair
rRNA processing
protein phosphorylation
endocytosis
microtubule nucleation
Golgi organization
signal transduction
regulation of cell shape
Wnt signaling pathway
peptidyl-serine phosphorylation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
circadian regulation of gene expression
protein localization to Golgi apparatus
nonmotile primary cilium assembly
regulation of circadian rhythm
COPII vesicle coating
spindle assembly
protein localization to cilium
protein localization to centrosome
positive regulation of canonical Wnt signaling pathway
cell-cell adhesion
cellular response to nerve growth factor stimulus
positive regulation of non-canonical Wnt signaling pathway
mitotic cell cycle
phosphorylation
rhythmic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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