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Proteintech
FKBP8 Monoclonal Antibody (1C1G12), CoraLite® Plus 488
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FIGURE: 1 / 1
FKBP8 Antibody (CL488-66690) in Flow
1X10^6 A431 cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-Human FKBP8 (CL488-66690, Clone:1C1G12) (red), or 0.4 µg Control Antibody. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL488-66690
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1C1G12
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MGQPPAEEAE QPGALAREFL AAMEPEPAPA PAPEEWLDIL GNGLLRKKTL VPGPPGSSRP VKGQVVTVHL QTSLENGTRV QEEPELVFTL GDCDVIQALD LSVPLMDVGE TAMVTADSKY CYGPQGRSPY IPPHAALCLE VTLKTAVDGP DLEMLTGQER VALANRKREC GNAHYQRADF VLAANSYDLA IKAITSSAKV DMTFEEEAQL LQLKVKCLNN LAASQLKLDH YRAALRSCSL VLEHQPDNIK ALFRKGKVLA QQGEYSEAIP ILRAALKLEP SNKTIHAELS KLVKKHAAQR STETALYRKM LGNPSRLPAK CPGKGAWSIP WKWLFGATAV ALGGVALSVV IAARN
Target Information
FKBP8 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, it does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 38 kDa FK506-binding protein; 38 kDa FKBP; FK506 binding protein 8, 38kDa; FK506-binding protein 38; FK506-binding protein 8; FKBP-38; FKBP-8; FKBP-type PPIase; FKBPR38; hFKBP38; mFKBP38; molecular chaperone FKBP38; Peptidyl-prolyl cis-trans isomerase FKBP8; PPIase FKBP8; Rotamase; unnamed protein product
Gene Aliases: 38kDa; FKBP-38; FKBP-8; FKBP38; FKBP8; FKBPr38; Sam11
UniProt ID: (Human) Q14318, (Mouse) O35465
Entrez Gene ID: (Human) 23770, (Mouse) 14232
cell fate specification
negative regulation of protein phosphorylation
protein folding
apoptotic process
signal transduction
smoothened signaling pathway
dorsal/ventral pattern formation
regulation of gene expression
dorsal/ventral neural tube patterning
neural tube development
BMP signaling pathway
regulation of BMP signaling pathway
positive regulation of BMP signaling pathway
multicellular organism growth
intracellular signal transduction
camera-type eye development
negative regulation of apoptotic process
neuron fate specification
regulation of macromolecule metabolic process
protein localization to mitochondrion
regulation of mitophagy
protein peptidyl-prolyl isomerization
chaperone-mediated protein folding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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