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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
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Protein Aliases: dimethylaniline monooxygenase [N-oxide-forming] 2; dimethylaniline oxidase 2; flavin containing monooxygenase 2; flavin containing monooxygenase 2 (non-functional); FMO 2; FMO, pulmonary; pulmonary flavin-containing monooxygenase 2; unnamed protein product
Gene Aliases: 2310008D08Rik; 2310042I22Rik; FMO1B1
UniProt ID: (Human) Q99518, (Mouse) Q8K2I3
Entrez Gene ID: (Human) 2327, (Pig) 100525884, (Mouse) 55990
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