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Proteintech
ATG9A Monoclonal Antibody (1D12E11), CoraLite® Plus 488
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Product Details
CL488-67096
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1D12E11
Immunogen
Recombinant Protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Target Information
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Apg9 plays a direct role in the formation of the cytoplasm to vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apg9; APG9 autophagy 9-like 1; APG9-like 1; Apg911; APG9A; ATG 9A; ATG9 autophagy related 9 homolog A; autophagy 9-like 1 protein; Autophagy-related protein 9A; FLJ22169; mATG9; unnamed protein product
Gene Aliases: APG9L1; ATG9A; mATG9; MGD3208
UniProt ID: (Human) Q7Z3C6
Entrez Gene ID: (Human) 79065
autophagosome assembly
mitophagy
lipid transport
autophagy
negative regulation of macrophage cytokine production
phospholipid scrambling
negative regulation of interferon-beta production
protein localization to Golgi apparatus
protein localization to pre-autophagosomal structure
piecemeal microautophagy of nucleus
innate immune response
bone morphogenesis
reticulophagy
programmed necrotic cell death
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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