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Proteintech
KMT2C Recombinant Rabbit Monoclonal Antibody (240542A2), CoraLite® Plus 488
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Product Details
CL488-83595-4
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
240542A2
Immunogen
KMT2C fusion protein Ag28875
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: SMFNEELDLP IDDKLDNQCV SVEPKKKEQE NKTLVLSDKH SPQKKSTVTN EVKTEVLSPN SKVESKCETE KNDENKDNVD TPCSQASAHS DLNDGEKTSL HPCDPDLFEK RTNRETAGPS ANVIQASTQL PAQDVINSCG ITGSTPVLSS LLANEKSDNS DIRPSGSPPP PTLPASPSNH VSSLPPFIAP PGRVLDNAMN SNVTVVSRVN HVFSQGVQVN PGLIPGQSTV
Target Information
Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2.1.1.43; ALR-like protein; Histone-lysine N-methyltransferase 2C; histone-lysine N-methyltransferase MLL3; histone-lysine N-methyltransferase, H3 lysine-4 specific; Homologous to ALR protein; lysine (K)-specific methyltransferase 2C; Lysine N-methyltransferase 2C; Myeloid/lymphoid or mixed-lineage leukemia protein 3; unnamed protein product
Gene Aliases: HALR; KIAA1506; KLEFS2; KMT2C; MLL3
UniProt ID: (Human) Q8NEZ4
Entrez Gene ID: (Human) 58508
DNA binding
transcription coactivator activity
RNA binding
protein binding
methyltransferase activity
zinc ion binding
transferase activity
transferase activity, transferring acyl groups
histone methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
metal ion binding
histone H3K4 monomethyltransferase activity
histone H3K4 trimethyltransferase activity
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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