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Proteintech
CD354/TREM-1 Recombinant Rabbit Monoclonal Antibody (240219H1), CoraLite® Plus 488
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FIGURE: 1 / 1
CD354/TREM-1 Antibody (CL488-98022) in Flow
1x10^6 mouse splenocytes were surface stained with CoraLite® Plus 647 Anti-Mouse Ly-6G/Ly-6C (Gr-1) and 0.25 µg CoraLite® Plus 488 Anti-Mouse TREM-1/CD354 Rabbit Recombinant Antibody (CL488-98022, Clone: 240219H1), or Isotype Control. Cells were not fixed.
Product Details
CL488-98022
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
240219H1
Immunogen
Fusion Protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Wet ice
Target Information
TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD354; sCD354; soluble CD354; soluble TREM 1; soluble TREM1; sTREM 1; sTREM1; TREM; TREM-1; triggering receptor expressed in monocytes 1; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 1
Gene Aliases: Trem1
UniProt ID: (Mouse) Q9JKE2
Entrez Gene ID: (Mouse) 58217
positive regulation of defense response to virus by host
cytokine secretion involved in immune response
cell migration
neutrophil chemotaxis
cytokine metabolic process
chemokine metabolic process
neutrophil mediated killing of gram-negative bacterium
neutrophil extravasation
mitophagy in response to mitochondrial depolarization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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