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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • TMEM16B Antibodies

          Proteintech

          ANO2 Monoclonal Antibody (2F12G1), CoraLite® Plus 488

          View all (8) TMEM16B antibodies

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          Cite ANO2 Monoclonal Antibody (2F12G1), CoraLite® Plus 488

          • Antibody Testing Data (1)
          ANO2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          ANO2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          ANO2 Antibody (CL48867638100UL) in IHC (P)

          Immunofluorescent analysis of (4% PFA) fixed Mouse eye tissue using CoraLite 488 ANO2 antibody (Product # CL48867638100UL), Clone: 2F12G1 ) at dilution of 1:200. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ANO2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          CL48867638100UL

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Mouse / IgG2a

          Class

          Monoclonal

          Type

          Antibody

          Clone

          2F12G1

          Conjugate

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488
          • Unconjugated
          • CoraLite 594
          • Request custom conjugation

          Excitation/Emission Max

          493/522 nm

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.3, with 50% glycerol, 0.5% BSA

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles, store in dark

          Shipping conditions

          Wet ice

          Target Information

          Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC's but has different biophysical characteristics such as voltage dependence and unitary conductance.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: ano2; anoctamin 2 isoform Adelta4; anoctamin 2 isoform Bdelta4; anoctamin 2, calcium activated chloride channel; Anoctamin-2; Transmembrane protein 16B; transmembrane protein 16B (eight membrane-spanning domains)

          View more View less

          Gene Aliases: ANO2; BC033409; C12orf3; TMEM16B

          View more View less

          UniProt ID: (Human) Q9NQ90, (Mouse) Q8CFW1

          View more View less

          Entrez Gene ID: (Human) 57101, (Mouse) 243634

          View more View less

          Function(s)
          intracellular calcium activated chloride channel activity protein homodimerization activity protein heterodimerization activity chloride channel activity protein binding phospholipid scramblase activity
          Process(es)
          transport ion transport chloride transport chloride transmembrane transport ion transmembrane transport
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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