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Proteintech
ALPL Recombinant Rabbit Monoclonal Antibody (230212D5), CoraLite® Plus 750
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Product Details
CL750-82915-2
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
230212D5
Immunogen
ALPL fusion protein Ag1664
Conjugate
Excitation/Emission Max
755/780 nm
Form
Liquid
Concentration
1000 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: EKDPKYWRDQ AQETLKYALE LQKLNTNVAK NVIMFLGDGM GVSTVTAARI LKGQLHHNPG EETRLEMDKF PFVALSKTYN TNAQVPDSAG TATAYLCGVK ANEGTVGVSA ATERSRCNTT QGNEVTSILR WAKDAGKSVG IVTTTRVNHA TPSAAYAHSA DRDWYSDNEM PPEALSQGCK DIAYQLMHNI RDIDVIMGGG RKYMYPKNKT DVEYESDEKA RGTRLDGLDL VDTWKSFKPR YKHSHFIWNR TELLTLDPHN VDYLLGLFEP GDMQYELNRN NVTDPSLSEM VVVAIQILRK NPKGFFLL
Target Information
Alkaline phosphatase is a homodimeric protein enzyme (86 kDa), containing two zinc atoms crucial to its catalytic function per monomer, and it is optimally active at alkaline pH environments. The enzyme is found in prokaryotes and eukaryotes, with the same general function but in different structural forms suitable to organism's environment. ALP plays a role in liver metabolism and development within the skeleton. In bacteria, ALP acts as a source of inorganic phosphate. In yeast, ALP can be a useful protein for studying membrane protein sorting.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alkaline phosphatase liver/bone/kidney isozyme; alkaline phosphatase, liver/bone/kidney; Alkaline phosphatase, tissue-nonspecific isozyme; AP-TNAP; FLJ40094; FLJ93059; glycerophosphatase; liver/bone/kidney-type alkaline phosphatase; MGC161443; MGC167935; Phosphoamidase; Phosphocreatine phosphatase; tissue non-specific alkaline phosphatase; tissue-nonspecific ALP; unnamed protein product
Gene Aliases: ALPL; AP-TNAP; APTNAP; HOPS; HPPA; HPPC; HPPI; HPPO; TNALP; TNAP; TNS-ALP; TNSALP
UniProt ID: (Human) P05186
Entrez Gene ID: (Human) 249
alkaline phosphatase activity
inorganic diphosphatase activity
calcium ion binding
pyrophosphatase activity
hydrolase activity
phosphatase activity
ATPase activity
pyridoxal phosphatase activity
adenosine-diphosphatase activity
metal ion binding
phosphoamidase activity
phosphoethanolamine phosphatase activity
skeletal system development
osteoblast differentiation
endochondral ossification
developmental process involved in reproduction
cellular homeostasis
bone mineralization
biomineral tissue development
response to lipopolysaccharide
response to insulin
response to vitamin D
response to vitamin B6
response to macrophage colony-stimulating factor
pyridoxal phosphate metabolic process
response to antibiotic
response to glucocorticoid
phosphate ion homeostasis
calcium ion homeostasis
cementum mineralization
positive regulation of cold-induced thermogenesis
futile creatine cycle
inhibition of non-skeletal tissue mineralization
response to sodium phosphate
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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