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Proteintech
CLSTN2 Polyclonal Antibody
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Product Details
21436-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CLSTN2 fusion protein Ag16048
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: ATYEPYLVTN DWPIHPSHIA MQLTVGACWQ GGEVTKPQFA QFFHGSLASL TIRPGKMESQ KVISCLQACK EGLDINSLES LGQGIKYHFN PSQSILVMEG DDIGNINRAL QKVSYINSRQ FPTAGVRRLK VSSKVQCFGE DVCISIPEVD AYVMVLQAIE PRITLRGTDH FWRPAAQFES ARGVTLFPDI KIVSTFAKTE APGDVKTTDP KSEVLEEMLH NLDFCDILVI GGDLDPRQEC LELNHSELHQ RHLDATNSTA GYSIYGVGSM SRYEQVLHHI RYRNWRPASL EARRFRIKCS
Target Information
Calsyntenin 2 (CLSTN2) is a gene located on chromosome 3p22.2 that encodes a member of the calsyntenin family of proteins, which are characterized by their role in calcium binding and involvement in synaptic function and neural connectivity. CLSTN2 is predominantly expressed in the nervous system, where it contributes to synaptic organization and signaling processes essential for neural plasticity and cognitive functions. The protein is involved in mediating vesicular transport and axonal trafficking, influencing the establishment and maintenance of synaptic connections. Altered expression or mutations in CLSTN2 have been linked to neurological disorders, including Alzheimer's disease, suggesting its significance in maintaining neural circuit stability and memory processes. Current research continues to explore CLSTN2's functional roles in neurobiology, with potential therapeutic implications for enhancing synaptic function and addressing neurodegenerative conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alc-gamma; alcadein gamma; Alcadein-gamma; cadherin-related family member 13; Calsyntenin-2; CS2alcadein-gamma; FLJ39113; FLJ39499; MGC119560
Gene Aliases: 2900042C18Rik; AI448973; ALC-GAMMA; alcagamma; CDHR13; CLSTN2; CS2; Cst-2; CSTN2; Kiaa4134; mKIAA4134
UniProt ID: (Human) Q9H4D0, (Rat) Q8VDA1, (Mouse) Q9ER65
Entrez Gene ID: (Human) 64084, (Rat) 171394, (Mouse) 64085
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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