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Invitrogen
CLTC Polyclonal Antibody
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FIGURE: 1 / 1
CLTC Antibody (PA5-109558) in WB
Western blot analysis of CLTC in extracts of various cell lines. Samples were incubated with CLTC Polyclonal antibody (Product # PA5-109558) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-109558
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1550-1650 of human Clathrin heavy chain (NP_004850.1)
Conjugate
Form
Liquid
Concentration
0.67 mg/mL
Amount
67 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AEELLQWFLQ EEKRECFGAC LFTCYDLLRP DVVLETAWRH NIMDFAMPYF IQVMKEYLTK VDKLDASESL RKEEEQATET QPIVYGQPQL MLTAGPSVAV P
Target Information
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Clathrin heavy chain 1; Clathrin heavy chain 2; Clathrin heavy chain on chromosome 17; Clathrin heavy chain on chromosome 22; clathrin, heavy polypeptide (Hc); Clathrin, heavy polypeptide D; clathrin, heavy polypeptide-like 1; clathrin, heavy polypeptide-like 2; CLH-17; CLH-22; KIAA0034; unnamed protein product
Gene Aliases: 3110065L21Rik; CHC; CHC17; CHC22; CLH-17; CLH17; CLH22; CLTC; CLTCL; CLTCL1; CLTCL2; CLTD; Hc; KIAA0034; MRD56; R74732
UniProt ID: (Human) Q00610, (Human) P53675, (Rat) P11442, (Mouse) Q68FD5
Entrez Gene ID: (Human) 1213, (Human) 8218, (Rat) 54241, (Mouse) 67300
RNA binding
double-stranded RNA binding
structural molecule activity
protein binding
protein kinase binding
clathrin light chain binding
low-density lipoprotein particle receptor binding
disordered domain specific binding
ubiquitin-specific protease binding
protein C-terminus binding
ankyrin binding
heat shock protein binding
peptide binding
poly(A) RNA binding
vesicle coat protein
mitotic cell cycle
osteoblast differentiation
intracellular protein transport
receptor-mediated endocytosis
autophagy
vesicle-mediated transport
receptor internalization
transferrin transport
retrograde transport, endosome to Golgi
clathrin coat assembly
cell division
regulation of mitotic spindle organization
clathrin coat disassembly
clathrin-mediated endocytosis
amyloid-beta clearance by transcytosis
negative regulation of hyaluronan biosynthetic process
negative regulation of protein localization to plasma membrane
anatomical structure morphogenesis
positive regulation of glucose import
Golgi organization
mitotic nuclear division
mitotic spindle assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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